For instance, it may be surprising that women with localized breast cancer who are younger than 50 have a lower 5-year relative survival rate then women ages 50 and up. All rights reserved. The chemotherapy regimen consisted of paclitaxel after doxorubicin and cyclophosphamide. According to estimates, more than 3.1 million women in the United States have a history of breast cancer. 3 Things I Wish I Knew When I Was Diagnosed with HER2+ Breast Cancer. If breast cancer recurs, the new tumor must be tested so treatment can be reevaluated. Regional breast cancer has spread to nearby tissue or lymph nodes (stage IB, some IIA, some IIB, and all stage III). Peter A.S. Johnstone and Marilyn S. Norton, and Robert H. Riffenburgh, PhD., of 250 untreated breast cancer patients found that the median survival time was 2.7 years. In fact, most people treated for early stage HER2-positive breast cancer don’t relapse. They don’t tell the whole story. If your breast cancer is also HR-positive, hormonal therapy may help reduce the risk of recurrence.

Once treatment for nonmetastatic breast cancer ends, you’ll still need periodic testing for signs of recurrence. This means the numbers are based on women who were found to have breast cancer at least 5 years ago. A 2014 study of more than 4,000 women showed that trastuzumab significantly reduced recurrence and improved survival when added to chemotherapy in early stage HER2-positive breast cancer… Targeted therapies usually work from outside the cell to block the chemical signals that promote tumor growth. Similarly, stage IV cancer has a drastically lower survivability rate, and it does not improve without treatment. HR status and HER2 status can change. Right away, she questioned how she'd be able to maintain her life, be a parent. HER2-positive breast cancer is more aggressive and more likely to recur than HER2-negative breast cancer. Younger women are less likely to be diagnosed at an early stage compared to older women. Breast cancer is not a single disease. These are numbers researchers collect over many years in people with the same type of cancer. WebMD does not provide medical advice, diagnosis or treatment. Life Expectancy for Spinal & Brain Cancer, Early Stage Breast Cancer-Frequently Asked Questions. from the same institution. The good news is that recurrence is less likely today than ever before. If left untreated, a less advanced staging is a less certain indicator of life expectancy.

Here are three things she wishes she knew at diagnosis. It’s also tested for something called human epidermal growth factor receptor 2 (HER2).

Statistics are averages.

Targeted treatments for HER2-positive breast cancer include: Trastuzumab helps blocks cancer cells from receiving chemical signals that spur growth. This drug combines trastuzumab with a chemotherapy drug called emtansine. Neratinib is a year-long treatment that’s used in the early stages of HER2-positive breast cancer. A beginning stage I diagnoses is indicative of a small tumor that has not begun to spread throughout the body while a potentially terminal stage IV is an advanced cancer that may have spread to vital organs or large swaths of tissue. However, it’s more likely to affect younger women. Our website services, content, and products are for informational purposes only. © 2019 www.azcentral.com. Ask your doctor to explain cancer survival statistics and how they may apply to your situation. Along with tumor grade and cancer stage, HR and HER2 status help determine your treatment options. HER2-positive breast cancer generally responds well to chemotherapy. You’ve probably been given a number and letter for your cancer stage. This does not change the fact that people with a cancer diagnosis are still advised to seek treatment. A 2014 study of more than 4,000 women showed that trastuzumab significantly reduced recurrence and improved survival when added to chemotherapy in early stage HER2-positive breast cancer. Current studies on breast cancer survival rates apply to all types. In this Ask the Expert, Hope Qamoos, NP, answers your questions about HER2-positive breast cancer, including treatments, surgery, outlook, and more. In a few rare cases, women suffering from advanced breast cancer have experienced regressions. Hormone receptors are identified as estrogen (ER) and progesterone (PR).

Danielle Cooper was diagnosed with HER2-positive breast cancer in 2016. Of course, the vast majority of women in both groups were receiving treatment. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts. Every Moment Matters with HER2+ Breast Cancer, Planning for Your Future, Post Breast Cancer Diagnosis, Ask the Expert: What to Know About Your HER2+ Diagnosis.